STANDARDIZED EXTRACTS OF COLEUS FORSKOHLII
NufoTrimTM is a standardized extract obtained from the matured roots of aromatic perennial herb Coleus forskohlii. Forskoliin is the principal active ingredient found in coleus, a traditional Ayurvedic herb that has been a part of Indian medicine for centuries. Human studies have indicated that supplementation with C. forskohlii extract elicits favorable changes to body composition.
Coleus forskohlii has a rich diversity of ethnopharmacological applications including weight management, heart ailments, and hypo tension. Coleus is known to be used as a condiment in some parts of India. Forskolin and its derivatives inhibit platelet aggregation,mast cell degranulation, relaxes arteries, regulates insulin secretion and thyroid function, decrease adipose accumulation, reduce body weight and stimulates digestive enzymes secretion. It is used in skin care, treatment of cardiovascular and respiratory diseases, etc.
Potential candidate for topical administration in sunless tanning products and UV protection.
Coleus forskohlii is a perennial herb in a large genus of mints. It is an important traditional Ayurvedic herb that has been a part of Indian medicine for centuries. Coleus is the source of a unique substance known as FORSKOLIN.
The topical application of forskolin to a murine model with humanized skin and a mutant MC1R, has resulted in significant melanization. This study implied that forskolin is a potential candidate for clinical application in sunless tanning products as well as a topical small-molecule manipulation of pigmentation that would protect against UV-induced cutaneous DNA damage.
A Revolution in Weight Management
Forskolin directly, rapidly and reversibly activate adenylate cyclase, resulting in a remarkable increase in the intracellular cAMP level. cAMP increases the utilization of body fat, basal metabolic rate, and regulates the body’s thermogenic response to food. Thus, the forskolin supplement may lead to fat loss without muscle mass loss.
A topical cosmetic slimming product combining forskolin, tetrahydroxypropyl ethylenediamine, caffeine, carnitine, and retinol have been developed. Clinical trial on five selected parts of the body was conducted among 78 women. The formulation improved skin feature and significantly reduced fat in the circumference of abdomen, hips-buttocks, and waist
NufoTrim increases the activity of cyclic adenosine monophosphate (cAMP), a messenger molecule that helps regulate the metabolism of glucose, proteins, and lipids, as well as the function of hormones like adrenaline.
Helps to reduces waist and hip circumference & helps mitigate weight gain in overweight men and women.
Increases HDL levels.
Improves insulin levels and insulin resistance.
NufoTrim stimulate mood,
Effective against asthma
Effective against high blood pressure,
Helps reduces intraocular pressure
Increases the basal metabolic rate, appetite and energy use in the body through cAMP
NufoTrim has been shown to slow the proliferation rate of skin cells by improving the relative balance of cAMP to cGMP